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. 1976 Nov;3(4):271-4.
doi: 10.1017/s0317167100025440.

Quebec cooperative study of Friedreich's ataxia: design of the investigation

Quebec cooperative study of Friedreich's ataxia: design of the investigation

A Barbeau. Can J Neurol Sci. 1976 Nov.

Abstract

The general outline of the complete prospective study of 50 cases of spino-cerebellar degeneration is given. The general protocol followed, the criteria for inclusion and the mode of analysis are described. The aim of this study was to establish a base of clinical, physiological and biochemical facts upon which a logical and systematic approach to pathogenesis and treatment of Friedreich's ataxia could be attempted.

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