Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1999 Feb 11;9(3):R106-9.
doi: 10.1016/s0960-9822(99)80062-1.

Alzheimer's disease: clues from flies and worms

B H Anderton  1
Affiliations
Free article
Review

Alzheimer's disease: clues from flies and worms

B H Anderton. Curr Biol. .
Free article

Abstract

Presenilin mutations give rise to familial Alzheimer's disease and result in elevated production of amyloid beta peptide. Recent evidence that presenilins act in developmental signalling pathways may be the key to understanding how senile plaques, neurofibrillary tangles and apoptosis are all biochemically linked.

PubMed Disclaimer

MeSH terms

Substances

LinkOut - more resources