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. 1976 Dec 29;35(1):79-82.
doi: 10.1007/BF00295621.

Localization of the Bf locus within the HLA region. Report on an informative family and critical evaluation of available data on Bf mapping

C Rittner, H Grosse-Wilde, E D Albert

Localization of the Bf locus within the HLA region. Report on an informative family and critical evaluation of available data on Bf mapping

C Rittner et al. Hum Genet. .

Abstract

Since the estimation of recombination fractions is only an arbitrary means to map genetic loci on chromosomal regions, family studies of cases with informative cross-overs within the region in question are of decisive importance. This paper reports the study of a family with a HLA-B to HLA-D cross-over which is informative in the Bf system. The possible reasons for conflicting published data on Bf gene mapping are discussed.

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