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Review
. 1999 Jan;86(1):8-17.
doi: 10.1007/s001140050562.

Characteristics of Filoviridae: Marburg and Ebola viruses

B Beer  1 , R Kurth, A Bukreyev
Affiliations
Review

Characteristics of Filoviridae: Marburg and Ebola viruses

B Beer et al. Naturwissenschaften. 1999 Jan.

Abstract

Filoviruses are enveloped, nonsegmented negative-stranded RNA viruses. The two species, Marburg and Ebola virus, are serologically, biochemically, and genetically distinct. Marburg virus was first isolated during an outbreak in Europe in 1967, and Ebola virus emerged in 1976 as the causative agent of two simultaneous outbreaks in southern Sudan and northern Zaire. Although the main route of infection is known to be person-to-person transmission by intimate contact, the natural reservoir for filoviruses still remains a mystery.

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