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Clinical Trial
. 1999 Feb;52(3):629-32.
doi: 10.1212/wnl.52.3.629.

Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

A I Qureshi  1 , M A Choudhry, M S Akbar, Y Mohammad, H C Chua, A M Yahia, J A Ulatowski, D A Krendel, R T Leshner
Affiliations
Clinical Trial

Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

A I Qureshi et al. Neurology. 1999 Feb.

Abstract

We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (i.v.Ig) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with i.v.Ig) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with i.v.Ig (13 versus 5 episodes, p = 0.07).

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