Chemotactic response of leukocytes to cord factor (trehalose-6,6'-dimycolate)
- PMID: 1003563
- DOI: 10.1093/jnci/57.6.1379
Chemotactic response of leukocytes to cord factor (trehalose-6,6'-dimycolate)
Abstract
Cord factor (trehalose-6,6'-dimycolate), a glycolipid extractable from myocobacteria, was chemotactic for peritoneal cells of mice at concentrations from 5 to 25 mug/ml medium, as well as for peripheral white blood cells of mice and humans. At higher concentrations, presumably only macrophages were attracted.
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