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Review
. 1999 Feb;11(1):28-33.
doi: 10.1016/s0952-7915(99)80006-5.

Lung surfactant proteins involved in innate immunity

P Eggleton  1 , K B Reid
Affiliations
Review

Lung surfactant proteins involved in innate immunity

P Eggleton et al. Curr Opin Immunol. 1999 Feb.

Abstract

The two lung surfactant collectins, surfactant protein (SP)-A and SP-D, are involved in host defence against infectious and allergenic agents via enhancement of killing and clearance by macrophages and neutrophils. Recent gene-knockout, protein engineering and physiological studies have emphasised the roles that SP-A and SP-D play in acute inflammatory responses.

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