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Review
. 1999 Feb;11(1):47-52.
doi: 10.1016/s0952-7915(99)80009-0.

Phagocytosis and development: back to the future

N C Franc  1 , K White, R A Ezekowitz
Affiliations
Review

Phagocytosis and development: back to the future

N C Franc et al. Curr Opin Immunol. 1999 Feb.

Abstract

Removal of apoptotic cells and micro-organisms is mediated via phagocytosis. Phagocytes express pattern-recognition receptors (PRRs) that recognize apoptotic-cell-associated membrane patterns (ACAMPs). Similar ACAMPs and PRRs are used by mammals, Caenorhabditis elegans and Drosophila melanogaster. Some PRRs recognize apoptotic cells and micro-organisms, suggesting overlap between these functions.

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