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. 1999 Mar 1;255(1):86-93.
doi: 10.1006/viro.1998.9557.

A new picornavirus isolated from bank voles (Clethrionomys glareolus)

B Niklasson  1 , L Kinnunen, B Hörnfeldt, J Hörling, C Benemar, K O Hedlund, L Matskova, T Hyypiä, G Winberg
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Free article

A new picornavirus isolated from bank voles (Clethrionomys glareolus)

B Niklasson et al. Virology. .
Free article

Abstract

A previously unknown picornavirus was isolated from bank voles (Clethrionomys glareolus). Electron microscopy images and sequence data of the prototype isolate, named Ljungan virus, showed that it is a picornavirus. The amino acid sequences of predicted Ljungan virus capsid proteins VP2 and VP3 were closely related to the human pathogen echovirus 22 (approximately 70% similarity). A partial 5' noncoding region sequence of Ljungan virus showed the highest degree of relatedness to cardioviruses. Two additional isolates were serologically and molecularly related to the prototype.

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