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Case Reports
. 1976;17(1-2):11-31.
doi: 10.1007/978-3-642-66312-3_2.

The preleukemic syndrome: clinical and laboratory features, natural course, and management

J W Linman, C Bagby Jr
Case Reports

The preleukemic syndrome: clinical and laboratory features, natural course, and management

J W Linman et al. Nouv Rev Fr Hematol Blood Cells. 1976.

Abstract

The clinical and laboratory features of the stages in the evolution of acute nonlymphocytic leukemia are reviewed. Based on a retrospective analysis of 34 patients who died with an acute myelomonoblastic leukemia, the "preleukemic syndrome" has been shown to display a clinical picture sufficiently specific to permit its recognition prospectively (i.e., before the development of overt leukemia). The results to date of a variety of prospective studies are reviewed, and the approach(es) to the management of these cases is considered.

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