[Consequences of the administration of alpha or beta drenolytic agents on the mobilization of plasma free fatty acids as induced by noradrenaline and isoprenaline in the dog]
- PMID: 10055
[Consequences of the administration of alpha or beta drenolytic agents on the mobilization of plasma free fatty acids as induced by noradrenaline and isoprenaline in the dog]
Abstract
Noradrénaline or isoprenaline (a beta sympathicomimetic drug) infusion in fasting awake dog provoque a rise of plasmatic FFA. This effect is abolished by administration of propranolol (beta blocking agent) but not by phentolamine (alpha blocking agent). Phentolamine potentiate the rise of FFA in response to noradrenaline but not to isoprenaline. This alpha blocking drug supress the fall of FFA induced by phenylephrine a sympathomimetic drug.