Animal models of human cholesterol gallstone disease: a review
- PMID: 100653
Animal models of human cholesterol gallstone disease: a review
Abstract
Human cholesterol gallstone disease has been a frequent and serious problem. A number of animal models have been reviewed for comparative study of cholesterol lithogenesis. These models in general have involved (1) decreasing bile salt excretion, (2) increasing dietary cholesterol, or (3) inducing gallbladder infection or stasis.