T-cell transformation by Marek's disease virus
- PMID: 10068994
- DOI: 10.1016/s0966-842x(98)01427-9
T-cell transformation by Marek's disease virus
Abstract
Marek's disease virus (MDV) is an avian herpesvirus that causes rapid development of T-cell lymphomas in chickens. The MDV genes currently thought to be involved in lymphomagenesis include a bZIP transactivator that is homologous to fos and jun oncogenes but do not appear to have counterparts in other oncogenic herpesviruses.
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