Review
doi: 10.1016/s0966-842x(98)01424-3.
Escherichia coli mutator genes
Affiliations
- PMID: 10068995
- DOI: 10.1016/s0966-842x(98)01424-3
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Review
Escherichia coli mutator genes
Trends Microbiol.
1999 Jan.
Abstract
The isolation and characterization of Escherichia coli mutator genes have led to a better understanding of DNA replication fidelity mechanisms and to the discovery of important DNA repair pathways and their relationship to spontaneous mutagenesis. Mutator strains in a population of cells can be beneficial in that they allow rapid selection of variants during periods of stress, such as drug exposure.
Comment in
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Sequence variation in Helicobacter pylori.Trends Microbiol. 2000 Feb;8(2):57-8. doi: 10.1016/s0966-842x(99)01676-5. Trends Microbiol. 2000. PMID: 10664596 No abstract available.
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