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Review
. 1999 Jan;7(1):29-36.
doi: 10.1016/s0966-842x(98)01424-3.

Escherichia coli mutator genes

J P Horst  1 , T H Wu, M G Marinus
Affiliations
Review

Escherichia coli mutator genes

J P Horst et al. Trends Microbiol. 1999 Jan.

Abstract

The isolation and characterization of Escherichia coli mutator genes have led to a better understanding of DNA replication fidelity mechanisms and to the discovery of important DNA repair pathways and their relationship to spontaneous mutagenesis. Mutator strains in a population of cells can be beneficial in that they allow rapid selection of variants during periods of stress, such as drug exposure.

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Comment in

  • Sequence variation in Helicobacter pylori.
    Achtman M, Suerbaum S. Achtman M, et al. Trends Microbiol. 2000 Feb;8(2):57-8. doi: 10.1016/s0966-842x(99)01676-5. Trends Microbiol. 2000. PMID: 10664596 No abstract available.

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