Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1997 Mar;18(2):112-4.

Rapid detoxification of heroin dependence by buprenorphine

Z M Liu  1 , Z J Cai, X P Wang, Y Ge, C M Li
Affiliations
  • PMID: 10072959
Free article
Comparative Study

Rapid detoxification of heroin dependence by buprenorphine

Z M Liu et al. Zhongguo Yao Li Xue Bao. 1997 Mar.
Free article

Abstract

Aim: To evaluate the clinical efficacy of buprenorphine (Bup) in treatment of acute heroin withdrawal.

Methods: Bup was given sublingually daily to 60 cases of heroin addicts in 3 groups: low, medium, and high doses. Withdrawal signs and symptoms of heroin were rated by Clinical Institute Narcotic Assessment. Craving for heroin during detoxification was assessed by Visual Analogue Scale. The side effects of Bup was assessed by Treatment Emergent Symptom Scale.

Results: The mean daily consumption of Bup in low, medium, and high group was 2.0, 2.9, and 3.6 mg, respectively. Bup not only suppressed objective signs and withdrawal symptoms for heroin withdrawal, but also reduced the duration for heroin detoxification over 7-8 d.

Conclusion: Bup is an effective and rapid detoxification agent with fewer side effects for treatment of acute heroin withdrawal.

PubMed Disclaimer

Publication types

LinkOut - more resources