Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Apr;37(4):1217-20.
doi: 10.1128/JCM.37.4.1217-1220.1999.

Identification of a novel genotype of hepatitis G virus in Southeast Asia

Affiliations

Identification of a novel genotype of hepatitis G virus in Southeast Asia

H Naito et al. J Clin Microbiol. 1999 Apr.

Abstract

Hepatitis G virus (HGV) isolates obtained from 20 Myanmarese and 10 Vietnamese subjects were analyzed. A cluster of isolates not belonging to any known genotype of HGV was found in five Myanmarese subjects and three Vietnamese subjects by phylogenetic analysis, and we classified this new genotype as type 4. These results revealed that the HGV genome can be classified into at least four major genotypes.

PubMed Disclaimer

Figures

FIG. 1
FIG. 1
Alignment of nucleotide sequences of the HGV 5′ UTR isolated from Myanmarese and Vietnamese subjects. Sources of all isolates with the accession numbers are described in the text. The nucleotide positions are based on those of the HGV PNF2161 isolate. Dashes indicate nucleotides that are identical to the top sequence (HGV PNF2161), and deletions of nucleotides are indicated by slashes. USA, United States.
FIG. 2
FIG. 2
Phylograms generated by neighbor-joining analysis of genetic distances in the 5′ UTR of HGV/GBV-C isolates. Database-derived HGV/GBV-C isolates are presented in italics. The numbers are percentages of bootstrap replicates supporting these branches.

References

    1. Abe K, Moriyama M, Hayashi S, Nakai K, Miyauchi I, Edamoto Y, Saito T, Fukushima S, Shimizu T, Matsumura H, Arakawa Y. Prevalence of hepatitis G virus infection among patients with liver diseases in Japan. Int Hepatol Commun. 1997;6:239–248.
    1. Alter H J, Nakatsuji Y, Melpolder J, Wages J, Wesley R, Shih W-K, Kim J P. The incidence of transfusion-associated hepatitis G virus infection and its relation to liver disease. N Engl J Med. 1997;336:747–754. - PubMed
    1. Alter M J, Gallagher M, Morris T T, Moyer L A, Meeks E L, Krawczynski K, Kim J P, Margolis H S. Acute non-A-E hepatitis in the United States and the role of hepatitis G virus infection. N Engl J Med. 1997;336:741–746. - PubMed
    1. Billis D M, Bull J J. An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis. Syst Biol. 1993;42:182–192.
    1. Erker J C, Simons J N, Muerhoff A S, Leary T P, Chalmers M L, Desai S M, Mushahwar I K. Molecular cloning and characterization of a GB virus C isolate from a patient with non-A-E hepatitis. J Gen Virol. 1996;77:2713–2720. - PubMed

Publication types

Associated data

LinkOut - more resources