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. 1999 Feb;62(2):324-6.
doi: 10.1021/np980286+.

Sideroxylonal C, a new inhibitor of human plasminogen activator inhibitor type-1, from the flowers of Eucalyptus albens

J Neve  1 , P A Leone, A R Carroll, R W Moni, N J Paczkowski, G Pierens, P Björquist, J Deinum, J Ehnebom, T Inghardt, G Guymer, P Grimshaw, R J Quinn
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Sideroxylonal C, a new inhibitor of human plasminogen activator inhibitor type-1, from the flowers of Eucalyptus albens

J Neve et al. J Nat Prod. 1999 Feb.

Abstract

Sideroxylonal C (3), a new phloroglucinol dimer, was isolated from the flowers of Eucalyptus albens through bioassay-guided fractionation. The structure elucidation was based on 1D and 2D NMR experiments, MS analysis, and comparison with sideroxylonals A (1) and B (2). Sideroxylonal C inhibited human plasminogen activator inhibitor type-1 at 4.7 microM without any significant effect on human tissue plasminogen activator.

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