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. 1978 Sep;75(9):4509-13.
doi: 10.1073/pnas.75.9.4509.

Somatostatin inhibits release of thyrotropin releasing factor from organ cultures of rat hypothalamus

Y Hirooka, C S Hollander, S Suzuki, P Ferdinand, S I Juan

Somatostatin inhibits release of thyrotropin releasing factor from organ cultures of rat hypothalamus

Y Hirooka et al. Proc Natl Acad Sci U S A. 1978 Sep.

Abstract

Somatostatin in concentrations of 10(-6) to 10(-8) M inhibited basal release of thyrotropin releasing factor in organ culture of rat hypothalamus. Norepinephrine in doses of 10(-4)--10(-6) M induced release of thyrotropin releasing factor which increased progressively with time and was temperature and dose dependent. This enhanced thyrotropin-releasing-factor release was inhibited by somatostatin at 10(-6)--10(-8) M.

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References

    1. Proc Natl Acad Sci U S A. 1975 Apr;72(4):1340-3 - PubMed
    1. Recent Prog Horm Res. 1975;31:365-97 - PubMed
    1. Endocrinology. 1975 Jun;96(6):1456-61 - PubMed
    1. Methods Enzymol. 1975;37:3-22 - PubMed
    1. J Clin Endocrinol Metab. 1975 Jul;41(1):168-71 - PubMed

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