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. 1976 Nov;6(6):690-3.
doi: 10.1007/BF02026089.

Does the pro-inflammatory factor in lymphocytes (LpIF) explain the role of these cells in acute inflammation?

R R Santos, J G Leme, S H Ferreira, G H Bechara, L Sudo

Does the pro-inflammatory factor in lymphocytes (LpIF) explain the role of these cells in acute inflammation?

R R Santos et al. Agents Actions. 1976 Nov.

Abstract

Lymphocytes produce a pro-inflammatory factor, which modulates the development of acute inflammation. Injection of lymphocytes or products, obtained from either rats, dogs or rabbits, caused a restoration of inflammatory responses in leukopenic rats which are hyporeactive to various inflammatory stimuli. In vitro incubation of viable lymphocytes with homologous and heterologous anti-lymphocyte sera abolished the ability of the cells to restore the inhibited inflammatory reactions.

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