Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Nov;66(5):448-51.

Effect of secretin, glucagon and duodenal acidification on bombesin-induced hypergastrinemia in man

N Basso, S Giri, E Lezoche, A Materia, P Melchiorri, V Speranza
  • PMID: 1008044

Effect of secretin, glucagon and duodenal acidification on bombesin-induced hypergastrinemia in man

N Basso et al. Am J Gastroenterol. 1976 Nov.

Abstract

The action of duodenal acidification, of continuous I.V. infusion of secretin and glucagon and of a one bolus I.V. administration of secretin and glucagon at maximal doses on BBS-induced gastrin secretion has been studied in a group of 18 healthy subjects. Continuous infusion of secretin and glucagon and the acidification of the duodenum did not alter significantly the levels of gastrin stimulated by BBS. Secretin and glucagon administered by a single I.V. bolus paritially inhibit the effect of BBS on gastrin levels. On the basis of these results it is not possible to affirm or to exclude the possibility that BBS is a hormone physiologically present in man.

PubMed Disclaimer