Seasonal plasticity of neuromuscular junctions in adult male Siberian hamsters (Phodopus sungorus)

Abstract

Transfer of adult Siberian hamsters, Phodopus sungorus, from long day (16 h light and 8 h dark; 16L:8D) to short day (8L:16D) photoperiods induces an involution of the gonads and a cessation of reproductive behavior 8-10 weeks later. The motoneurons of the spinal nucleus of the bulbocavernosus and their target muscles, the bulbocavernosus and the levator ani, are sexually dimorphic and are necessary for successful reproduction by male mammals. We demonstrate that after transfer of adult male Siberian hamsters to short photoperiods, the bulbocavernosus motoneurons, their target muscles and neuromuscular junctions are all significantly smaller than those of males that remain under long day conditions. Photoperiod also affected the number of active zones within each neuromuscular junction, an apparent remodeling of these synapses. Thus, this neuromuscular system of adult Siberian hamsters demonstrates considerable seasonal plasticity in response to changes in photoperiod.