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. 1976 Nov;51(11):875-8.
doi: 10.1136/adc.51.11.875.

Estimation of glomerular filtration rate from plasma creatinine concentration in children

R Counahan, C Chantler, S Ghazali, B Kirkwood, F Rose, T M Barratt

Estimation of glomerular filtration rate from plasma creatinine concentration in children

R Counahan et al. Arch Dis Child. 1976 Nov.

Abstract

The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour creatinine clearance. It was found to be superior to the creatinine clearance overall, and was as good, even if all results involving suspect 24-hour-urine collections were eliminated from analysis. The formula in SI usage is: GFR/SA (ml/min per 1-73 m2SA) = 38 Ht (cm)1Pc (mumol/l).

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