Future prospects for artificial blood
- PMID: 10087605
- DOI: 10.1016/s0167-7799(98)01242-6
Future prospects for artificial blood
Abstract
Concern about potential infective agents in donated blood has stimulated the recent development of blood substitutes. Chemically cross-linked hemoglobins are already undergoing clinical trials and might soon be ready for routine use. New generations of modified hemoglobin are being prepared to modulate the effects of nitric oxide and oxygen radicals, and artificial red blood cells are also under development.
Similar articles
-
Future generations of red blood cell substitutes.J Intern Med. 2003 May;253(5):527-35. doi: 10.1046/j.1365-2796.2003.01151.x. J Intern Med. 2003. PMID: 12702030 Review.
-
Artificial Oxygen Carriers: Exactly How Close Are We to an Ultimate Product?Artif Organs. 2017 Apr;41(4):316-318. doi: 10.1111/aor.12939. Artif Organs. 2017. PMID: 28397406 No abstract available.
-
[Hemoglobin-based oxygen carriers and trials to substitute red blood cells].Transfus Clin Biol. 2007 Nov;14(5):464-73. doi: 10.1016/j.tracli.2007.12.007. Epub 2008 Mar 4. Transfus Clin Biol. 2007. PMID: 18295525 Review. French.
-
Modified hemoglobin-based blood substitutes: crosslinked, recombinant and encapsulated hemoglobin.Vox Sang. 1998;74 Suppl 2:233-41. doi: 10.1111/j.1423-0410.1998.tb05425.x. Vox Sang. 1998. PMID: 9704450 Review.
-
[Current aspects in red blood cell substitutes].Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2004 Jun;21(3):490-4. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2004. PMID: 15250164 Review. Chinese.
Cited by
-
Drugs for increasing oxygen and their potential use in doping: a review.Sports Med. 2003;33(3):187-212. doi: 10.2165/00007256-200333030-00003. Sports Med. 2003. PMID: 12656640 Review.
-
Potentials and limitations of microorganisms as renal failure biotherapeutics.Biologics. 2009;3:233-43. Epub 2009 Jul 13. Biologics. 2009. PMID: 19707412 Free PMC article.
-
Extension arm facilitated PEGylation of hemoglobin: correlation of the properties with the extent of PEGylation.Protein J. 2006 Jun;25(4):263-74. doi: 10.1007/s10930-006-9010-y. Protein J. 2006. PMID: 16718519
-
Influence of the chemistry of conjugation of poly(ethylene glycol) to Hb on the oxygen-binding and solution properties of the PEG-Hb conjugate.Biochem J. 2005 Dec 15;392(Pt 3):555-64. doi: 10.1042/BJ20050663. Biochem J. 2005. PMID: 16111474 Free PMC article.
-
Non-hypertensive tetraPEGylated canine haemoglobin: correlation between PEGylation, O2 affinity and tissue oxygenation.Biochem J. 2007 Aug 1;405(3):503-11. doi: 10.1042/BJ20070238. Biochem J. 2007. PMID: 17425516 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources