Collagen synthesis and deposition in cartilage during disrupted proteoglycan production
- PMID: 1008841
- PMCID: PMC1164207
- DOI: 10.1042/bj1600117
Collagen synthesis and deposition in cartilage during disrupted proteoglycan production
Abstract
A simple system was developed to investigate in vitro the possible relationship between collagen and proteoglycan synthesis in cartilage. When production of complete proteoglycan molecules was effectively inhibited with 4-methylumbelliferyl beta-D-xyloside collagen synthesis and distribution were virtually unaffected.
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