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. 1976 Oct 15;160(1):117-20.
doi: 10.1042/bj1600117.

Collagen synthesis and deposition in cartilage during disrupted proteoglycan production

P Dondi, H Muir

Collagen synthesis and deposition in cartilage during disrupted proteoglycan production

P Dondi et al. Biochem J. .

Abstract

A simple system was developed to investigate in vitro the possible relationship between collagen and proteoglycan synthesis in cartilage. When production of complete proteoglycan molecules was effectively inhibited with 4-methylumbelliferyl beta-D-xyloside collagen synthesis and distribution were virtually unaffected.

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