Macro creatine kinase in Kawasaki disease

Abstract

This report describes a case of Kawasaki disease with macro creatine kinase (CK). A 13-month-old boy developed typical symptoms of Kawasaki disease and was treated with flurbiprofen, dipyridamole, and intravenous gamma-globulin. The serum level of CK increased during treatment from 371 U/L, at 4 days after the onset of Kawasaki disease, to 13,222 U/L 3 days later. Immunofixation electrophoresis identified macro CK as containing immunoglobulin A (kappa, lambda). The presence of macro CK may result from muscle tissue involvement in Kawasaki disease.