[Angiogenesis in brain neoplasms--biological and clinical aspects]
- PMID: 10093477
[Angiogenesis in brain neoplasms--biological and clinical aspects]
Abstract
Solid tumors are dependent on angiogenesis for sustained growth, therefore anti-angiogenic treatment is a potential antineoplastic therapy. Glioblastoma multiforme has been considered a suitable candidate for such treatment. This review summarizes the fundamentals of angiogenic process in glioblastoma multiforme and in other types of brain tumors for which they represent a potential for anti-angiogenic therapy.
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