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. 1999 Jan;191(1-2):105-9.

Searching interaction partners of protein kinase CK2beta subunit by two-hybrid screening

S Grein  1 , K Raymond, C Cochet, W Pyerin, E M Chambaz, O Filhol
Affiliations
  • PMID: 10094398

Searching interaction partners of protein kinase CK2beta subunit by two-hybrid screening

S Grein et al. Mol Cell Biochem. 1999 Jan.

Abstract

To date, the intracellular regulation of protein kinase CK2 is unknown. However it was observed that the enzyme associates with several intracellular proteins and the formation of such molecular complexes may represent a mechanism for the control of CK2 activity. Using the Interaction Trap system in yeast, with the CK2beta as a bait, we looked for CK2 partners. We present the identification of new potential partners of CK2beta and it is hoped that their classification will help in understanding the physiological roles and the regulation of CK2 in the cell.

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