Microbial polyketide synthases: more and more prolific

Review

C R Hutchinson. Proc Natl Acad Sci U S A. 1999.

. 1999 Mar 30;96(7):3336-8.

doi: 10.1073/pnas.96.7.3336.

No abstract available

Figures

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.
McDaniel R, Thamchaipenet A, Gustafsson C, Fu H, Betlach M, Ashley G. McDaniel R, et al. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1846-51. doi: 10.1073/pnas.96.5.1846. Proc Natl Acad Sci U S A. 1999. PMID: 10051557 Free PMC article.
Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes.
Shen Y, Yoon P, Yu TW, Floss HG, Hopwood D, Moore BS. Shen Y, et al. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3622-7. doi: 10.1073/pnas.96.7.3622. Proc Natl Acad Sci U S A. 1999. PMID: 10097087 Free PMC article.

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