Review
doi: 10.1016/s0950-3536(98)80063-2.
The haemolytic-uraemic syndrome in childhood
Affiliations
- PMID: 10097822
- DOI: 10.1016/s0950-3536(98)80063-2
Item in Clipboard
Review
The haemolytic-uraemic syndrome in childhood
Baillieres Clin Haematol.
1998 Jun.
Abstract
Haemolytic-uraemic syndrome (HUS) is a clinical syndrome characterized by acute haemolytic anaemia with fragmented erythocytes, thrombocytopenia and acute renal failure. It is one of the leading causes of acute renal failure in childhood. HUS in children can be divided into the so-called typical, diarrhoea-associated HUS, and atypical HUS, which is not preceded by acute gastroenteritis. Infection with verocytotoxin-producing Escherichia coli is the main cause of diarrhoea-associated HUS. In this chapter the pathogenesis of diarrhoea-associated HUS and the role of verocytotoxin-producing Escherichia coli in this form of HUS is emphasized.
Similar articles
-
[Infections with verocytotoxin-producing Escherichia coli and hemolytic-uremic syndrome].Ned Tijdschr Geneeskd. 1996 Jan 20;140(3):134-7. Ned Tijdschr Geneeskd. 1996. PMID: 8618631 Review. Dutch.
-
Clinical features, therapeutic interventions and long-term aspects of hemolytic-uremic syndrome in Norwegian children: a nationwide retrospective study from 1999-2008.BMC Infect Dis. 2016 Jun 13;16:285. doi: 10.1186/s12879-016-1627-7. BMC Infect Dis. 2016. PMID: 27297224 Free PMC article.
-
Verocytotoxin-producing Escherichia coli and the haemolytic uraemic syndrome.J Infect. 1995 May;30(3):189-92. doi: 10.1016/s0163-4453(95)90601-0. J Infect. 1995. PMID: 7673740 No abstract available.
-
A prospective study of exposure to verotoxin-producing Escherichia coli among Canadian children with haemolytic uraemic syndrome. The CPKDRC co-investigators.Epidemiol Infect. 1993 Feb;110(1):1-7. doi: 10.1017/s0950268800050615. Epidemiol Infect. 1993. PMID: 8432313 Free PMC article.
-
Eculizumab in the treatment of Shiga toxin haemolytic uraemic syndrome.Pediatr Nephrol. 2019 Sep;34(9):1485-1492. doi: 10.1007/s00467-018-4025-0. Epub 2018 Jul 30. Pediatr Nephrol. 2019. PMID: 30058046 Free PMC article. Review.