High-resolution electrocardiography

Abstract

High-resolution electrocardiography, often referred to as signal averaged electrocardiography (SAECG), has clinical utility in human medicine for detecting ventricular late potentials (LP) as predictors of future arrhythmic events, specifically reentrant type of ventricular tachycardia (VT). Time-domain analysis of the SAECG is conceptually similar to standard ECG analysis, but the primary objective is to detect LP, the marker for reentrant pathways within the myocardium. Frequency-domain analysis is investigational but provides the same information as time-domain analysis and both methods of analysis have limitations. The presence of LP has been associated with the ability to induce VT, unexplained syncope, and sudden arrhythmic death. Some cardiomyopathic dogs with VT have SAECG that appear to contain LP, and sudden death has occurred in these dogs.