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Clinical Trial
. 1999 Mar;87(3):362-5.
doi: 10.1016/s1079-2104(99)70224-6.

A comparison of 2 topical anesthetics on the discomfort of intraligamentary injections: a double-blind, split-mouth volunteer clinical trial

J G Meechan  1 , J M Thomason
Affiliations
Clinical Trial

A comparison of 2 topical anesthetics on the discomfort of intraligamentary injections: a double-blind, split-mouth volunteer clinical trial

J G Meechan et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Mar.

Abstract

Objective: The purpose of this volunteer clinical trial was to compare the effects of 5% lidocaine ointment and EMLA cream on the discomfort associated with intraligamentary injections.

Study design: A double-blind, split mouth study was conducted. Each of 10 healthy volunteers had 5% lidocaine and EMLA cream applied to the maxillary premolar buccal gingiva for 5 minutes before the administration of an intraligamentary injection. Discomfort during the injection was assessed through use of a visual analog scale. Data were analyzed by means of Student paired and unpaired t tests.

Results: Injection discomfort on the side on which EMLA cream was applied was significantly less than on the lidocaine side (t = 2.32, P < .05).

Conclusions: EMLA cream reduced the discomfort associated with intraligamentary injections.

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