Plaque-forming cells in mice after experimental infection with Brucella abortus
- PMID: 101461
- PMCID: PMC421995
- DOI: 10.1128/iai.21.1.337-339.1978
Plaque-forming cells in mice after experimental infection with Brucella abortus
Abstract
Cells producing antibody to brucella lipopolysaccharide were detected in spleens of mice infected with Brucella abortus 19 by a hemolytic plaque assay. The appearance of immunoglobulin M-producing cells preceded humoral antibodies. The primary plaques were observed 5 days after inoculation, and they were still present by day 70.
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