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. 1978 Jul;21(1):337-9.
doi: 10.1128/iai.21.1.337-339.1978.

Plaque-forming cells in mice after experimental infection with Brucella abortus

Plaque-forming cells in mice after experimental infection with Brucella abortus

S Schneerson-Porat et al. Infect Immun. 1978 Jul.

Abstract

Cells producing antibody to brucella lipopolysaccharide were detected in spleens of mice infected with Brucella abortus 19 by a hemolytic plaque assay. The appearance of immunoglobulin M-producing cells preceded humoral antibodies. The primary plaques were observed 5 days after inoculation, and they were still present by day 70.

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