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. 1976 Oct 15;32(10):1246-9.
doi: 10.1007/BF01953073.

Regulation of enzymes of ethanol metabolism in yeast (Rhodotorula gracilis)

G M Hanozet, M Simonetta, D Barisio, A Guerritore

Regulation of enzymes of ethanol metabolism in yeast (Rhodotorula gracilis)

G M Hanozet et al. Experientia. .

Abstract

The three enzymes of ethanol metabolism alcohol dehydrogenase, aldehyde dehydrogenase and acetyl-CoA synthetase in the obligate aerobic yeast Rhodotorula gracilis are repressed by glucose and induced by C2 metabolic fuels with a regulatory pattern indicating a correlation in the control mechanisms. To try an identification of the molecular signals involved in the transmission of the inducing stimulus, experiments were carried out by blocking with 2 mM pyrazole the ethanol acetaldehyde metabolic step. Results indicate that ethanol is not specifically required as a molecular signal for induction.

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