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. 1999 Feb;25(1):66-70.
doi: 10.1053/ejso.1998.0602.

Survival after radical treatment for transitional cell carcinoma of the bladder

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Survival after radical treatment for transitional cell carcinoma of the bladder

L Daehlin et al. Eur J Surg Oncol. 1999 Feb.

Abstract

Aims: To investigate survival after radical treatment for transitional cell carcinomas of the bladder.

Methods: This retrospective study included 135 patients with transitional cell carcinoma of the bladder undergoing radical cystectomy or radiotherapy at Haukeland Hospital, Bergen, Norway, during the period 1981-1986. Forty-five patients had cystectomy and 90 underwent external high-dose radiotherapy.

Results: The overall 5- and 10-year survival rates were 39 and 23%, respectively. After cystectomy 10-year overall survival rates for superficial and muscle-infiltrating tumours were 67 and 26%; after radiotherapy, the corresponding survival rates for superficial and muscle-infiltrating tumours were 26 and 5%, respectively.

Conclusions: Long-term survival and cure can be achieved after cystectomy in many patients with aggressive superficial or muscle-infiltrating bladder carcinoma. The introduction of orthotopic neobladder reconstruction should encourage the use of cystectomy in patients with aggressive superficial tumour.

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