Comment on

• Prevention of cardiac hypertrophy by calcineurin inhibition: hope or hype?

  Olson EN, Molkentin JD. Olson EN, et al. Circ Res. 1999 Apr 2;84(6):623-32. doi: 10.1161/01.res.84.6.623. Circ Res. 1999. PMID: 10189350 Review. No abstract available.
• Signaling in myocardial hypertrophy: life after calcineurin?

  Sugden PH. Sugden PH. Circ Res. 1999 Apr 2;84(6):633-46. doi: 10.1161/01.res.84.6.633. Circ Res. 1999. PMID: 10189351 Review. No abstract available.
• Failure of calcineurin inhibitors to prevent pressure-overload left ventricular hypertrophy in rats.

  Zhang W, Kowal RC, Rusnak F, Sikkink RA, Olson EN, Victor RG. Zhang W, et al. Circ Res. 1999 Apr 2;84(6):722-8. doi: 10.1161/01.res.84.6.722. Circ Res. 1999. PMID: 10189360
• Pressure overload induces severe hypertrophy in mice treated with cyclosporine, an inhibitor of calcineurin.

  Ding B, Price RL, Borg TK, Weinberg EO, Halloran PF, Lorell BH. Ding B, et al. Circ Res. 1999 Apr 2;84(6):729-34. doi: 10.1161/01.res.84.6.729. Circ Res. 1999. PMID: 10189361
• Cyclosporine attenuates pressure-overload hypertrophy in mice while enhancing susceptibility to decompensation and heart failure.

  Meguro T, Hong C, Asai K, Takagi G, McKinsey TA, Olson EN, Vatner SF. Meguro T, et al. Circ Res. 1999 Apr 2;84(6):735-40. doi: 10.1161/01.res.84.6.735. Circ Res. 1999. PMID: 10189362