Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1998 Nov;79(3):F212-4.
doi: 10.1136/fn.79.3.f212.

Influence of erythromycin on establishment of feeding in preterm infants: observations from a randomised controlled trial

B J Stenson  1 , L Middlemist, A J Lyon
Affiliations
Clinical Trial

Influence of erythromycin on establishment of feeding in preterm infants: observations from a randomised controlled trial

B J Stenson et al. Arch Dis Child Fetal Neonatal Ed. 1998 Nov.

Abstract

Aim: To determine the effect of erythromycin on the establishment of enteral feeding in ventilated infants < 31 weeks gestation.

Methods: Erythromycin was randomly allocated as an antimicrobial treatment for the first 7 days of life in 76 infants: 35 received erythromycin and 41 acted as controls. Feed toleration, time taken to establish full enteral feeding, vomiting, prescription of glycerine suppositories and occurrence of necrotising enterocolitis were recorded.

Results: There were no significant differences between the groups for any of the outcomes. The infants treated with erythromycin reached full feeding at a median (quartile) age of 8 (5-12) days compared with 9 (6-14) days for controls.

Conclusions: Intravenous erythromycin in antimicrobial doses is unlikely to benefit the introduction of feeding in preterm infants.

PubMed Disclaimer

References

    1. Biol Neonate. 1993;63(6):349-52 - PubMed
    1. Am J Physiol. 1990 Sep;259(3 Pt 1):G355-63 - PubMed
    1. J Pediatr. 1989 Oct;115(4):646-51 - PubMed
    1. Am J Physiol. 1989 Sep;257(3 Pt 1):G470-4 - PubMed
    1. Gut. 1988 Apr;29(4):483-8 - PubMed

Publication types