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Review
. 1999 Apr 10;318(7189):991-4.
doi: 10.1136/bmj.318.7189.991.

Recent advances in haematology

Affiliations
Review

Recent advances in haematology

D Provan et al. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Transferrin receptor expressed on cell surface binds transferrin bound to two iron atoms. The transferrin receptor-transferrin complex is internalised; iron dissociates and moves into cytosol; and transferrin receptor-transferrin complex moves back to plasma membrane and dissociates (TfR=transferrin receptor; monoFeTf=transferrin bound to one iron atom; diFeTf=transferrin bound to two iron atoms; apoTf=transferrin lacking bound iron; H+=hydrogen ion)
Figure 2
Figure 2
GeneChip array (Affymetrix), a closed system containing many oligonucleotides on a lawn to which test DNA is added, has potential to screen for large numbers of mutations. Figure shows the closed chip, the lawn to which test samples hybridise, and magnified view of result for p53 analysis

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