Motor unit double discharges: statistical anomaly or functional entity?

Abstract

Motor unit double discharges, or doublets, have been described as two consecutive motor unit discharges that occur with a short interspike interval of 2.5 - 20 ms (Simpson, 1969). Double discharges have been reported in the literature for over 70 years. For instance, Eccles and Hoff (1932) found that double discharges were elicited occasionally at the onset of a crossed extension reflex in the soleus muscle of the anaesthetized cat. With the use of electrical stimulation protocols, short interspike intervals inserted at the beginning of a stimulation train have been shown to increase both the peak force and rate of rise of force production, and also decrease the range of fatigue. The extent to which double discharges occur in naturally-occurring voluntary behaviours remains relatively unexplored. This review examines the issue of whether double discharges occur solely because of an intrinsic property of motoneurones, thereby representing a "statistical anomaly," or whether they may result from a neural control strategy to augment force production, i.e., a "functional entity."