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Review
. 1999 Mar;28(1):1-25, v.
doi: 10.1016/s0889-8553(05)70041-8.

Regulation of bile acid biosynthesis

Z R Vlahcevic  1 , W M Pandak, R T Stravitz
Affiliations
Review

Regulation of bile acid biosynthesis

Z R Vlahcevic et al. Gastroenterol Clin North Am. 1999 Mar.

Abstract

This article provides a review of the pathways through which cholesterol is degraded to bile acids. Regulation of key enzymes in the bile acid biosynthestic pathways is discussed. The important role of these pathways in the maintenance of cholesterol homeostasis and the possible therapeutic implications for the treatment of hypercholesterolemia are emphasized.

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