Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1999 Mar;29(3):147-52.
doi: 10.1007/s002470050560.

CT scan patterns of pulmonary alveolar proteinosis in children

V Albafouille  1 , N Sayegh, S De Coudenhove, P Scheinmann, J De Blic, T Mamou-Mani, A Hassine, F Jaubert, F Brunelle
Affiliations
Case Reports

CT scan patterns of pulmonary alveolar proteinosis in children

V Albafouille et al. Pediatr Radiol. 1999 Mar.

Abstract

Background: To study computed tomographic (CT) findings in children with pulmonary alveolar proteinosis (PAP) more extensively.

Objective: To describe the CT features at the time of diagnosis and after therapeutic broncho-alveolar lavage (BAL).

Materials and methods: We retrospectively reviewed the CT scans of five children (aged 3 months to 4 years) examined because of incidental bronchitis (n = 1), disease in a sibling (n = 1) and relapsing fever, cough and dyspnoea (n = 3). Each patient had an initial CT scan. Two asymptomatic cases were not treated but were followed up by plain chest films. The other three had BAL and follow-up CT.

Results: Initial CT in all cases showed a diffuse reticulomicronodular pattern associated in three cases with posterior bilateral alveolar infiltrates. CT in the two asymptomatic patients remained unchanged or slightly improved without BAL. After BAL, a variable decrease of lung infiltrates was observed.

Conclusions: Correlation between the extent of alveolar consolidation and severity of disease was found. Anatomical and pathological considerations allow us to consider that the classical reticulomicronodular pattern is not due to an interstitial infiltration but to alveoli filled with the abnormal material characteristic of PAP.

PubMed Disclaimer