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. 1999 Mar;20(3):114-8.
doi: 10.1016/s0167-5699(98)01393-0.

An innate view of human pregnancy

G Sacks  1 , I Sargent, C Redman
Affiliations

An innate view of human pregnancy

G Sacks et al. Immunol Today. 1999 Mar.

Abstract

Our understanding of the immunology of pregnancy has been dominated by the fetal allograft model and by changes in the maternal-specific immune system. Here, Gavin Sacks and colleagues draw attention to substantial and contrasting changes in the maternal innate system and hypothesize that its function and that of monocytes in particular, has a central role in the maternal-fetal relationship.

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Comment in

  • Th2-deviation of fetus-specific T cells.
    Ekerfelt C, Matthiesen L, Berg G, Ernerudh J. Ekerfelt C, et al. Immunol Today. 1999 Nov;20(11):534. doi: 10.1016/s0167-5699(99)01511-x. Immunol Today. 1999. PMID: 10529783 No abstract available.
  • Innate immunity in pregnancy.
    Sacks G, Sargent I, Redman C. Sacks G, et al. Immunol Today. 2000 Apr;21(4):200-1. doi: 10.1016/s0167-5699(00)01615-7. Immunol Today. 2000. PMID: 10740247 No abstract available.

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