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Case Reports
. 1999 Mar;41(3):195-8.
doi: 10.1007/s002340050733.

High-intensity basal ganglia lesions on T1-weighted images in two toddlers with elevated blood manganese with portosystemic shunts

K Ihara  1 , T Hijii, R Kuromaru, M Ariyoshi, R Kira, J Fukushige, T Hara
Affiliations
Case Reports

High-intensity basal ganglia lesions on T1-weighted images in two toddlers with elevated blood manganese with portosystemic shunts

K Ihara et al. Neuroradiology. 1999 Mar.

Abstract

We report two toddlers with portosystemic shunts who had symmetrical high-signal globus pallidus lesions on T1- but not T2-weighted MRI, and measurement of whole blood manganese at 2 years of age. These cases suggest that portosystemic shunts can cause elevation of blood manganese and result in manganese accumulation in the globus pallidus, causing high signal on T1-weighted images even in asymptomatic toddlers.

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