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. 1999 Apr;66(2):159-60.
doi: 10.1053/rvsc.1998.0255.

The pharmacokinetics of promethazine after intravenous administration in camels

I A Wasfi  1 , I M Barezaiq, N Alkatheeri, A A Hadi, N S Boni, A M Almuhrami, M Elghazali
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The pharmacokinetics of promethazine after intravenous administration in camels

I A Wasfi et al. Res Vet Sci. 1999 Apr.

Abstract

The pharmacokinetics of promethazine were determined in seven camels (Camelus dromedarius) after an intravenous dose of 0.5 mg kg body weight.-1 The data obtained (median and range) were as follows: the elimination half-life (t1/2 beta) was 5.62 (2.84-6.51) h; the steady state volume of distribution (Vdss) was 8.90 (7.10-12.00) L kg-1, total body clearance (CT) was 24.5 (17.22-33.65) ml kg-1 min-1 and renal clearance (Clr) was 4.81 (1.97-5.48) ml kg-1 min-1.

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