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Review
. 1999 Mar 25;9(6):R198-200.
doi: 10.1016/s0960-9822(99)80128-6.

RNA splicing: What has phosphorylation got to do with it?

T Misteli  1
Affiliations
Free article
Review

RNA splicing: What has phosphorylation got to do with it?

T Misteli. Curr Biol. .
Free article

Abstract

Many pre-mRNA splicing factors are phosphorylated in vivo, but the role of this modification has been unclear. Recent observations suggest that phosphorylation modulates protein-protein interactions within the spliceosome, thereby contributing to dynamic structural reorganization of the spliceosome during splicing.

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