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Review
. 1999 Feb;10(2):147-53.
doi: 10.1097/00001813-199902000-00002.

Role of red blood cells in pharmacokinetics of chemotherapeutic agents

D Schrijvers  1 , M Highley, E De Bruyn, A T Van Oosterom, J B Vermorken
Affiliations
Review

Role of red blood cells in pharmacokinetics of chemotherapeutic agents

D Schrijvers et al. Anticancer Drugs. 1999 Feb.

Abstract

After oral or parenteral administration of chemotherapeutic agents, these drugs are transported to the tissues by the blood in different fractions: plasma water, plasma proteins or cells. In this review, the role of the red blood cell in storage, transport and metabolism of different anti-cancer drugs is described.

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