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Review
. 1999 Apr 24;318(7191):1118-21.
doi: 10.1136/bmj.318.7191.1118.

Motor neurone disease

Affiliations
Review

Motor neurone disease

P J Shaw. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Major factors that seem to be contributing to motor neurone injury and the cell specific features of motor neurones that may render these cells vulnerable to such insults
Figure 2
Figure 2
Evidence for alteration in the glutamate neurotransmitter system in motor neurone disease

References

    1. Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, et al. Mutations in Cu/Zn superoxide dismutase are associated with familial amyotrophic lateral sclerosis. Nature. 1993;362:59–62. - PubMed
    1. Cookson MR, Shaw PJ. Oxidative stress and motor neurone disease. Brain Pathol (in press). - PMC - PubMed
    1. Brown RH. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell. 1995;80:687–692. - PubMed
    1. Hentati A, Bejaoui K, Pericak-Vance M, Hentati F, Speer MC, Hung WY, et al. Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35. Nat Genet. 1994;7:425–428. - PubMed
    1. Chance PF, Rabin BA, Ryan SG, Ding Y, Scavina M, Crain B, et al. Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34. Am J Hum Genet. 1998;62:633–640. - PMC - PubMed

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