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Case Reports
. 1999 Apr 12;52(6):1282-4.
doi: 10.1212/wnl.52.6.1282.

Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barré syndrome

M Mori  1 , S Kuwabara, M Miyake, M Dezawa, E Adachi-Usami, H Kuroki, M Noda, T Hattori
Affiliations
Case Reports

Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barré syndrome

M Mori et al. Neurology. .

Abstract

The authors report a patient with an axonal Guillain-Barré syndrome (acute motor axonal neuropathy) associated with anti-GM1 antibody after Haemophilus influenzae infection. The result of ELISA inhibition studies and cytochemical staining with cholera toxin suggest the presence of a GM1-like structure on the surface of H. influenzae isolated from the patient. A particular strain of H. influenzae may have a GM1-like structure and may elicit an axonal Guillain-Barré syndrome.

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