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. 1999 Apr;62(4):619-21.
doi: 10.1021/np980375m.

10'-Hydroxyusambarensine, a new antimalarial bisindole alkaloid from the roots of Strychnos usambarensis

M Frédérich  1 , M Tits, M P Hayette, V Brandt, J Penelle, P DeMol, G Llabrès, L Angenot
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Free article

10'-Hydroxyusambarensine, a new antimalarial bisindole alkaloid from the roots of Strychnos usambarensis

M Frédérich et al. J Nat Prod. 1999 Apr.
Free article

Abstract

Reinvestigation of Strychnos usambarensis Gilg resulted in the isolation of a tertiary phenolic bisindole alkaloid, 10'-hydroxyusambarensine (1), which was identified by detailed spectroscopic methods. Compound 1 was moderately active against two strains of Plasmodium falciparum in vitro.

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